National Repository of Grey Literature 3 records found  Search took 0.01 seconds. 
Formation of blastema during limb regeneration in Amphibia
Paušlyová, Lucia ; Tlapáková, Tereza (advisor) ; Paňková, Daniela (referee)
Total limb regeneration among vertebrates is basically restricted to some amphibians. Urodeles have the ability to regenerate amputated limbs through their life span. Anurans have the ability of complete regeneration of amputated limbs only in their larval stage. The key process of the limb regeneration is the formation of undifferentiated cell group which is called blastema. There are many cell types that contribute to formation of the blastema while the most important part in this process belongs to the skeleton muscle tissue and dermal fibroblasts. Another critical factor in formation of the blastema and its growth are the nerves in the area of wound and neurotrophic factors produced by them. In the last 20 years it has been great improvement in using different markers for tracking the fate of blastema cells.
Regeneration abilities among vertebrates
Majerová, Veronika ; Starostová, Zuzana (advisor) ; Soukup, Vladimír (referee)
Among vertebrates the ability to regenerate various body structure, from the cellular level to diverse internal organs or even the complex body structures (such as limb or tail), is unequally distributed across animal taxa. Regeneration is understood as the restoration of damaged or completely lost tissues, while the restored structure is more or less similar or even identical to the original structure. Regeneration is naturally often preceded by an encounter with a predator, when the animal is directly injured by the predator or an autotomy may occur as an anti-predator mechanism, which means that the animal voluntarily releases an appendage. Autotomy and following regeneration have many advantages but there can also appear some costs associated with these events which may have various consequences Masters in regeneration are considered to be mainly urodele amphibians who are able to perfectly regenerate various body structures (such as eye lens, limb or tail) and this ability persists throughout their lives, unlike anuran amphibians, in which the ability to regenerate after metamorphosis decreases significantly. In contrast to amphibians, the ability to regenerate among mammals or birds is severely limited. The aim of this work is to approach the ability of regeneration and the mechanisms by...
Formation of blastema during limb regeneration in Amphibia
Paušlyová, Lucia ; Tlapáková, Tereza (advisor) ; Paňková, Daniela (referee)
Total limb regeneration among vertebrates is basically restricted to some amphibians. Urodeles have the ability to regenerate amputated limbs through their life span. Anurans have the ability of complete regeneration of amputated limbs only in their larval stage. The key process of the limb regeneration is the formation of undifferentiated cell group which is called blastema. There are many cell types that contribute to formation of the blastema while the most important part in this process belongs to the skeleton muscle tissue and dermal fibroblasts. Another critical factor in formation of the blastema and its growth are the nerves in the area of wound and neurotrophic factors produced by them. In the last 20 years it has been great improvement in using different markers for tracking the fate of blastema cells.

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